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US launches Precision Strike Missiles in Iran war in first combat use
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US launches Precision Strike Missiles in Iran war in first combat use

Jimmie Dempsey
Last updated: March 4, 2026 8:43 pm
Jimmie Dempsey Published March 4, 2026
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The U.S. military recently deployed Lockheed Martin’s long-range Precision Strike Missile, or PrSM, for the first time in combat against Iranian targets, U.S. Central Command announced.

Video released Wednesday shows the next-gen munitions being launched in open desert terrain from M142 High Mobility Artillery Rocket Systems as part of Operation Epic Fury. The operation against Iran has seen a variety of precision munitions launched from land, sea and air, according to CENTCOM.

“I just could not be prouder of our men and women in uniform leveraging innovation to create dilemmas for the enemy,” Adm. Brad Cooper, CENTCOM commander, said in a release.

The PrSM is enhanced with GPS capabilities to navigate in flight and can accurately strike targets from around 250 miles away. Its warhead is designed to deliver a fragmentation effect when it explodes, increasing power on impact. The missile, meanwhile, is reportedly built to withstand turbulent in-flight conditions.

The PrSM is among a wide array of advanced technological assets the U.S. military has deployed during its ongoing operations in Iran.

Other notable weapon deployments in the ongoing conflict include Patriot Interceptor Missile Systems and THAAD Anti-Ballistic Missile Systems. LUCAS one-way attack drones were also used for the first time in combat by the U.S. Special Operations Command-led Task Force Scorpion Strike.

Specific details about the targets engaged by the PrSMs have not been provided as of publication.

Prior to its combat debut, the U.S. Army was working with Lockheed Martin to ramp up production capacity for the munition, Defense News reported last October.

The Army tested its short-range and long-range capabilities on White Sands Missile Range in April and September of last year. Tests saw the munitions fired from HIMARS systems as well as the M270A2 Multiple Launch Rocket System, or MLRS.

Operation Epic Fury has seen over 2,000 military targets across Iran destroyed, the Pentagon said, including a naval frigate that was sunk in the first torpedo kill by a U.S. Navy submarine since World War II.

About Zita Ballinger Fletcher

Zita Ballinger Fletcher previously served as editor of Military History Quarterly and Vietnam magazines and as the historian of the U.S. Drug Enforcement Administration. She holds an M.A. with distinction in military history.

Read the full article here

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